Tadalafil, the main ingredient in Vidalista 20mg, helps men achieve erections and enhances their sexual lives. Engaging in moderate physical activity for at least 30 to 60 minutes can help you maintain or improve your endurance and reduce your risk of erectile dysfunction. When a man is sexually excited, nitric oxide is released into the erectile tissue of the penis. The activation of guanylate cyclase by nitric oxide causes an increase in cGMP levels. It is extremely forbidden to combine pills with grapefruit juice or alcohol. Some of the negative effects of Vidalista 20mg include headaches, nausea, back pain, blurred vision, and flushing in the face, neck, or chest. The medicine will not work as well if you consume grapefruit juice or alcohol. Be cautious to drink plenty of water when taking this medication.